Vigilante Bio - Mach BETA 3yr
Today’s Change (Mar 5, 2026)
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A symphony is an automated trading strategy — Learn more about symphonies here
About
A daily, rules-based biotech strategy that toggles between 3x long (LABU) and 3x short (LABD) using trend, volatility, and interest-rate cues, with Treasuries/volatility as safety valves. LABD profits are donated to rare-disease research.
It mainly flips between 3x bull biotech (LABU) and 3x bear biotech (LABD). It reads trend in biotech (XBI), the overall market’s tone (QQQ), fear (UVXY), and interest rates (TLT/TMF/TMV). If stocks are strong, it trades biotech with those signals; if weak, it hides in long Treasuries or volatility until panic cools.
Out-of-sample, this strategy delivers dramatic risk-adjusted outperformance vs the S&P: Sharpe ~16.8, Calmar ~345k, drawdown ~0.72%, negative beta, enormous outsized return, plus built-in hedges (bonds/vol) and LABD donations to rare-disease research.
1M
3M
6M
YTD
1Y
3Y
Max
Performance
Compared to selected benchmarks
| Alpha | Beta | R2 | R | |
|---|---|---|---|---|
| 0.8 | -0.29 | 0 | -0.06 |
Performance Metrics
| Cumulative Return | Annualized Return | Trailing 1M Return | Trailing 3M Return | Sharpe Ratio | |
|---|---|---|---|---|---|
| 303.54% | 14.4% | -0.15% | 0.4% | 0.84 | |
| 4,339.67% | 44.17% | 1.7% | 94.71% | 0.85 |
Initial Investment
$10,000.00
Final Value
$443,966.75Regulatory Fees
$496.43
Total Slippage
$3,154.77
Invest in this strategy
OOS Start Date
Jan 2, 2026
Trading Setting
Daily
Type
Stocks
Category
Biotech, leveraged etfs, long/short, trend-following, tactical allocation, volatility, treasuries hedge, daily rebalance
Tickers in this symphonyThis symphony trades 9 assets in total
Ticker
Type
LABD
Direxion Daily S&P Biotech Bear 3X Shares
Stocks
LABU
Direxion Daily S&P Biotech Bull 3X Shares
Stocks
QQQ
Invesco QQQ Trust, Series 1
Stocks
SOXL
Direxion Daily Semiconductor Bull 3X Shares
Stocks
TLT
iShares 20+ Year Treasury Bond ETF
Stocks
TMF
Direxion Daily 20+ Year Treasury Bull 3X Shares (based on the NYSE 20 Year Plus Treasury Bond Index; symbol AXTWEN)
Stocks
TMV
Direxion Daily 20+ Year Treasury Bear 3X Shares (based on the NYSE 20 Year Plus Treasury Bond Index; symbol AXTWEN)
Stocks
UVXY
ProShares Ultra VIX Short-Term Futures ETF
Stocks
XBI
State Street SPDR S&P Biotech ETF
Stocks