Vigilante Bio - Mach BETA 3yr
Today’s Change (Nov 5, 2026)
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A symphony is an automated trading strategy — Learn more about symphonies here
About
An aggressive biotech trading system that flips between bullish and bearish 3x biotech funds based on market trend, volatility, and stress signals, with defensive moves into bonds or volatility during rough markets.
This strategy makes one big daily bet at a time, usually on biotech going up (LABU) or down (LABD). It first checks whether the broader growth-stock market looks healthy using QQQ, a big tech-heavy index. Then it looks for warning signs like sharp drops, unusual volatility, weak bonds, or biotech being too overheated. If danger is rising, it may short biotech or hide in bond or volatility funds instead.
Out-of-sample return: 16.94% vs S&P 15.78%; modest negative beta adds diversification. But max drawdown is much larger (~41.8% vs 8.9%). Biotech-driven, trend-following strategy aiming for stronger upside with macro hedges.
1M
3M
6M
YTD
1Y
3Y
Max
Performance
Compared to selected benchmarks
| Alpha | Beta | R2 | R | |
|---|---|---|---|---|
| 0.74 | -0.29 | 0 | -0.06 |
Performance Metrics
| Cumulative Return | Annualized Return | Trailing 1M Return | Trailing 3M Return | Sharpe Ratio | |
|---|---|---|---|---|---|
| 355.19% | 14.71% | -1.04% | -0.34% | 0.87 | |
| 3,231.38% | 37.36% | -16.72% | -16.34% | 0.8 |
Initial Investment
$10,000.00
Final Value
$333,137.62Regulatory Fees
$1,000.09
Total Slippage
$7,146.99
Invest in this strategy
OOS Start Date
Jan 2, 2026
Trading Setting
Daily
Type
Stocks
Category
Biotech, long-short, leveraged etfs, tactical asset allocation, trend-following, risk management, sector rotation
Tickers in this symphonyThis symphony trades 9 assets in total
Ticker
Type
LABD
Direxion Daily S&P Biotech Bear 3X ETF
Stocks
LABU
Direxion Daily S&P Biotech Bull 3X ETF
Stocks
QQQ
Invesco QQQ Trust, Series 1
Stocks
SOXL
Direxion Daily Semiconductor Bull 3X ETF
Stocks
TLT
iShares 20+ Year Treasury Bond ETF
Stocks
TMF
Direxion Daily 20+ Year Treasury Bull 3X ETF
Stocks
TMV
Direxion Daily 20+ Year Treasury Bear 3X ETF
Stocks
UVXY
ProShares Ultra VIX Short-Term Futures ETF
Stocks
XBI
State Street SPDR S&P Biotech ETF
Stocks