Healthcare - High Beta
Today’s Change (Mar 18, 2026)
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A symphony is an automated trading strategy — Learn more about symphonies here
About
A daily, rules-based switch. When biotech (XBI) is red‑hot, trending, and volatile, it buys 10 strong healthcare/biotech names. If not, it parks in a single defensive bond/defensive‑sector ETF picked by recent weakness.
It uses XBI (a biotech fund) as a thermometer. If biotech is extremely hot (RSI: recent gain speed >80), trending up (20‑day average gain >0), and very jumpy (high volatility), it buys 10 of the strongest healthcare/biotech names by recent momentum. Otherwise, it moves 100% into one “defensive” ETF (bonds or defensive sectors) that’s fallen the most recently (lowest RSI). Rebalanced daily.
Out-of-sample, this regime-switching healthcare/biotech strategy delivers superior risk-adjusted returns vs the S&P 500: Sharpe 2.47 vs 1.42, annualized return ~47% vs ~14%, Calmar ~11.45, beta ~0.44, with drawdowns ~4.1% vs ~2.6%.
1M
3M
6M
YTD
1Y
3Y
Max
Performance
Compared to selected benchmarks
| Alpha | Beta | R2 | R | |
|---|---|---|---|---|
| 0.27 | 0.43 | 0.19 | 0.44 |
Performance Metrics
| Cumulative Return | Annualized Return | Trailing 1M Return | Trailing 3M Return | Sharpe Ratio | |
|---|---|---|---|---|---|
| 62.63% | 11.15% | -1.77% | 0.2% | 0.7 | |
| 303.86% | 35.46% | -1.48% | 14.87% | 1.84 |
Initial Investment
$10,000.00
Final Value
$40,386.05Regulatory Fees
$307.73
Total Slippage
$1,825.52
Invest in this strategy
OOS Start Date
Nov 27, 2025
Trading Setting
Daily
Type
Stocks
Category
Healthcare, biotech, momentum, tactical, risk-on/risk-off, defensive rotation, leveraged etfs
Tickers in this symphonyThis symphony trades 42 assets in total
Ticker
Type
ABCL
AbCellera Biologics Inc. Common Shares
Stocks
ABSI
Absci Corporation Common Stock
Stocks
ALIT
Alight, Inc.
Stocks
ALNY
Alnylam Pharmaceuticals, Inc.
Stocks
AMGN
Amgen Inc
Stocks
ANGL
VanEck Fallen Angel High Yield Bond ETF
Stocks
ATOM
Atomera Incorporated Common Stock
Stocks
BFLY
Butterfly Network, Inc.
Stocks
BMRN
BioMarin Pharmaceuticals Inc
Stocks
BSV
Vanguard Short-Term Bond ETF
Stocks