BioTech v2
Today’s Change (Mar 18, 2026)
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A symphony is an automated trading strategy — Learn more about symphonies here
About
Rides biotech uptrends by owning the two strongest small/mid‑cap biotech stocks; in downtrends, rotates into two oversold defensive bond/sector funds. Simple trend and strength checks, equal weights, rebalanced monthly.
Once a month: 1) Check biotech’s trend using IBB. If its 50‑day average price is above its 200‑day average, biotech is “rising.” 2) If rising, buy two smaller biotech stocks with the strongest recent gains (RSI = a simple gauge of recent up vs down moves). 3) If not rising, buy two defensive bond/staples/utilities/healthcare funds with the weakest short‑term performance (lowest RSI), aiming for a bounce. Split 50/50 and rebalance monthly.
Out-of-sample, BioTech v2 tends to outperform in biotech uptrends with two momentum-driven biotech picks, while protecting in downturns by rotating to two defensive bond/sector funds. Simple, monthly, 2-holdings; aim for higher upside with clearer risk control vs. the S&P 500.
1M
3M
6M
YTD
1Y
3Y
Max
Performance
Compared to selected benchmarks
| Alpha | Beta | R2 | R | |
|---|---|---|---|---|
| 0.84 | 0.77 | 0.05 | 0.21 |
Performance Metrics
| Cumulative Return | Annualized Return | Trailing 1M Return | Trailing 3M Return | Sharpe Ratio | |
|---|---|---|---|---|---|
| 65.57% | 13.29% | -1.77% | 0.2% | 0.8 | |
| 2,053.56% | 113.8% | -4.99% | -18.23% | 1.47 |
Initial Investment
$10,000.00
Final Value
$215,356.33Regulatory Fees
$83.34
Total Slippage
$412.19
Invest in this strategy
OOS Start Date
Feb 27, 2026
Trading Setting
Monthly
Type
Stocks
Category
Biotech momentum, trend filter (50/200 ma), risk-off rotation, bonds and defensive sectors, monthly rebalance
Tickers in this symphonyThis symphony trades 20 assets in total
Ticker
Type
ACLX
Arcellx, Inc. Common Stock
Stocks
AVXL
Anavex Life Sciences
Stocks
BSV
Vanguard Short-Term Bond ETF
Stocks
IBB
iShares Biotechnology ETF
Stocks
LQD
iShares iBoxx $ Investment Grade Corporate Bond ETF
Stocks
NRSN
NeuroSense Therapeutics Ltd. Ordinary Shares
Stocks
PCVX
Vaxcyte, Inc. Common Stock
Stocks
PLUR
Pluri Inc. Common Stock
Stocks
RXRX
Recursion Pharmaceuticals, Inc. Class A Common Stock
Stocks
RZLT
Rezolute, Inc. Common Stock (NV)
Stocks