BioTech v2.1 86 | 31 | 2022
Today’s Change (Apr 29, 2026)
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A symphony is an automated trading strategy — Learn more about symphonies here
About
Own 3 strong biotech stocks when the biotech sector (IBB) is in an uptrend; otherwise rotate into bonds and defensive sector ETFs (some leveraged), picking the most oversold for bounce potential. Rebalances monthly.
Each month it checks if biotech is trending up by comparing IBB’s recent average price (50‑day) to its long‑term average (200‑day). If up, it buys 3 biotech stocks with the strongest recent price strength (RSI: higher = stronger). If not, it shifts to a 75/25 mix of bond/defensive ETFs, buying the two most beaten‑down names (low RSI) in each basket.
Out-of-sample testing shows this regime-switching biotech strategy beats the S&P 500: capture rallies with 3 momentum-biotech picks when IBB trends up, and cushion declines with a disciplined 75/25 defensive/bond rotation, monthly rebalanced.
1M
3M
6M
YTD
1Y
3Y
Max
Performance
Compared to selected benchmarks
| Alpha | Beta | R2 | R | |
|---|---|---|---|---|
| 0.59 | 0.93 | 0.11 | 0.33 |
Performance Metrics
| Cumulative Return | Annualized Return | Trailing 1M Return | Trailing 3M Return | Sharpe Ratio | |
|---|---|---|---|---|---|
| 76.15% | 14.6% | 12.61% | 2.62% | 0.86 | |
| 1,192.67% | 85.15% | -4.23% | 6.52% | 1.48 |
Initial Investment
$10,000.00
Final Value
$129,267.44Regulatory Fees
$43.97
Total Slippage
$258.92
Invest in this strategy
OOS Start Date
Apr 23, 2026
Trading Setting
Monthly
Type
Stocks
Category
Biotech, momentum, trend filter, sector rotation, rsi, defensive rotation, leveraged etfs, monthly rebalance
Tickers in this symphonyThis symphony trades 40 assets in total
Ticker
Type
ACLX
Arcellx, Inc. Common Stock
Stocks
ALNY
Alnylam Pharmaceuticals, Inc.
Stocks
AMGN
Amgen Inc
Stocks
ANGL
VanEck Fallen Angel High Yield Bond ETF
Stocks
ARGX
argenx SE American Depositary Shares
Stocks
AVXL
Anavex Life Sciences
Stocks
BIIB
Biogen Inc. Common Stock
Stocks
BND
Vanguard Total Bond Market
Stocks
CURE
Direxion Daily Healthcare Bull 3X ETF
Stocks
DRN
Direxion Daily Real Estate Bull 3X ETF
Stocks