BioTech v2
Today’s Change (Mar 15, 2026)
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A symphony is an automated trading strategy — Learn more about symphonies here
About
Tactical biotech strategy: if biotech is in an uptrend, hold the two strongest biotech names; otherwise rotate into the most oversold defensive ETFs (bonds and defensive sectors). Equal‑weighted, rebalanced monthly.
Each month it checks if biotech is rising using IBB (a biotech ETF): is the 50‑day average price above the 200‑day? If yes, buy the 2 biotech stocks with the strongest recent momentum by 14‑day RSI (a 0–100 gauge of recent gains). If not, buy 2 defensive ETFs (bonds, staples, utilities, health care) with the lowest 10‑day RSI (most beaten‑down). Equal‑weight; cash holds any leftover.
Out-of-sample stats suggest this strategy can outperform the S&P 500: it rides biotech leaders in uptrends and shifts to beaten-down defensive ETFs in downturns, with monthly rebalancing that trims risk and preserves capital.
1M
3M
6M
YTD
1Y
3Y
Max
Performance
Compared to selected benchmarks
| Alpha | Beta | R2 | R | |
|---|---|---|---|---|
| 0.84 | 0.77 | 0.05 | 0.21 |
Performance Metrics
| Cumulative Return | Annualized Return | Trailing 1M Return | Trailing 3M Return | Sharpe Ratio | |
|---|---|---|---|---|---|
| 63.48% | 12.96% | -2.85% | -2.42% | 0.78 | |
| 2,035.82% | 113.68% | -2.59% | -21.74% | 1.47 |
Initial Investment
$10,000.00
Final Value
$213,581.51Regulatory Fees
$83.34
Total Slippage
$412.19
Invest in this strategy
OOS Start Date
Feb 27, 2026
Trading Setting
Monthly
Type
Stocks
Category
Biotech, trend filter (50/200 ma), momentum (rsi), defensive rotation, tactical, monthly rebalance
Tickers in this symphonyThis symphony trades 20 assets in total
Ticker
Type
ACLX
Arcellx, Inc. Common Stock
Stocks
AVXL
Anavex Life Sciences
Stocks
BSV
Vanguard Short-Term Bond ETF
Stocks
IBB
iShares Biotechnology ETF
Stocks
LQD
iShares iBoxx $ Investment Grade Corporate Bond ETF
Stocks
NRSN
NeuroSense Therapeutics Ltd. Ordinary Shares
Stocks
PCVX
Vaxcyte, Inc. Common Stock
Stocks
PLUR
Pluri Inc. Common Stock
Stocks
RXRX
Recursion Pharmaceuticals, Inc. Class A Common Stock
Stocks
RZLT
Rezolute, Inc. Common Stock (NV)
Stocks